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Prediction of inadequate response (IR) in ERA was based on ROC analysis separated by stage I/II (1 and 26 patients) and stage III/IV disease (7 and 16 patients) or treatment group/level (TG/TL) 1 to 3. Early response assessment (ERA) was performed after 2 cycles of induction chemotherapy according to treatment protocol and verified by reference rating. Metabolic (SUVmax, SUVmean, SUVpeak, total lesion glycolysis ) and heterogeneity parameters (asphericity, entropy, contrast, local homogeneity, energy, and cumulative SUV-volume histograms) were derived. Total metabolic tumor volume (MTV) in pretherapeutic FDG-PET was defined using a semi-automated, background-adapted threshold. Retrospective analysis in 50 children with HL (f:18 m:32 median age, 14.8 a) consecutively treated according to EuroNet-PHL-C1 (n = 42) or -C2 treatment protocol (n = 8). We aimed to identify quantitative parameters from pretherapeutic FDG-PET to assist prediction of response to induction chemotherapy. For example, if you want to jump to, you can enter '50' under 'Search' menu simple.Standardized treatment in pediatric patients with Hodgkin's lymphoma (HL) follows risk stratification by tumor stage, erythrocyte sedimentation rate and tumor bulk.

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Pdf viewer for windows 7 1.0.320 free download